Genetic dosage and position effect of small supernumerary marker chromosome (sSMC) in human sperm nuclei in infertile male patient

Chromosomes occupy specific distinct areas in the nucleus of the sperm cell that may be altered in males with disrupted spermatogenesis. Here, we present alterations in the positioning of the human chromosomes 15, 18, X and Y between spermatozoa with the small supernumerary marker chromosome (sSMC;...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Olszewska, Marta, Wanowska, Elzbieta, Kishore, Archana, Huleyuk, Nataliya, Georgiadis, Andrew P., Yatsenko, Alexander N., Mikula, Mariya, Zastavna, Danuta, Wiland, Ewa, Kurpisz, Maciej
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4663790/
https://ncbi.nlm.nih.gov/pubmed/26616419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17408
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