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Imaging Reporters for Proteasome Activity Identify Tumor- and Metastasis-Initiating Cells
Tumor-initiating cells, also designated as cancer stem cells, are proposed to constitute a subpopulation of malignant cells central to tumorigenesis, metastasis, and treatment resistance. We analyzed activity of the proteasome, the primary organelle for targeted protein degradation, as a marker of t...
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| Publicado no: | Mol Imaging |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4663702/ https://ncbi.nlm.nih.gov/pubmed/26431589 |
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