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Phorbaketal A, Isolated from the Marine Sponge Phorbas sp., Exerts Its Anti-Inflammatory Effects via NF-κB Inhibition and Heme Oxygenase-1 Activation in Lipopolysaccharide-Stimulated Macrophages

Marine sponges harbor a range of biologically active compounds. Phorbaketal A is a tricyclic sesterterpenoid isolated from the marine sponge Phorbas sp.; however, little is known about its biological activities and associated molecular mechanisms. In this study, we examined the anti-inflammatory eff...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Seo, Yun-Ji, Lee, Kyung-Tae, Rho, Jung-Rae, Choi, Jung-Hye
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4663563/
https://ncbi.nlm.nih.gov/pubmed/26610528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md13117005
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