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Metformin suppressed the proliferation of LoVo cells and induced a time-dependent metabolic and transcriptional alteration
Metformin is a widely used anti-diabetic drug with potential anti-tumor activity. However, little is known about its global metabolic and transcriptional impacts on tumor cells. In current study, we performed a metabolic profiling on human-derived colon cancer LoVo cells treated by 10 mM metformin f...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4663508/ https://ncbi.nlm.nih.gov/pubmed/26616174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17423 |
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