ATM kinase is required for telomere elongation in mouse and human cells

Short telomeres induce a DNA damage response, senescence and apoptosis; thus, maintaining telomere length equilibrium is essential for cell viability. Telomerase addition of telomere repeats is tightly regulated in cells. To probe pathways that regulate telomere addition, we developed the ADDIT assa...

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Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Lee, Stella Suyong, Bohrson, Craig, Pike, Alexandra Mims, Wheelan, Sarah Jo, Greider, Carol Widney
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4663052/
https://ncbi.nlm.nih.gov/pubmed/26586427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.10.035
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