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Elevated glucose and angiotensin II increase 12-lipoxygenase activity and expression in porcine aortic smooth muscle cells.

The lipoxygenase (LO) pathway of arachidonate metabolism has been suggested to play a key role in atherosclerosis and in mediating several actions of angiotensin II (AII). However, the relationship between LO activation and factors linked to accelerated diabetic vascular disease such as hyperglycemi...

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Détails bibliographiques
Auteurs principaux: Natarajan, R, Gu, J L, Rossi, J, Gonzales, N, Lanting, L, Xu, L, Nadler, J
Format: Artigo
Langue:Inglês
Publié: 1993
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC46630/
https://ncbi.nlm.nih.gov/pubmed/8506339
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