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Comparative effectiveness and safety of indomethacin versus ibuprofen for the treatment of patent ductus arteriosus

BACKGROUND: Patent ductus arteriosus (PDA) is common in extremely premature infants and associated with increased morbidity and mortality. Medical management of PDA uses either indomethacin or ibuprofen. Despite numerous studies, uncertainty exists as to which drug is safer or more effective; we sou...

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Detalhes bibliográficos
Publicado no:Early Hum Dev
Main Authors: Gulack, Brian C., Laughon, Matthew M., Clark, Reese H., Sankar, Meera N., Hornik, Christoph P., Smith, P. Brian
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662898/
https://ncbi.nlm.nih.gov/pubmed/26386610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.earlhumdev.2015.08.003
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