An HLA-C amino-acid variant in addition to HLA-B*27 confers risk for ankylosing spondylitis in the Korean population

INTRODUCTION: The presence of the HLA-B*27 allele is a major risk factor for the development of ankylosing spondylitis (AS), which causes chronic inflammation of the spine and other sites. We investigated residual effects outside HLA-B within the major histocompatibility complex (MHC) region in the...

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Vydáno v:Arthritis Res Ther
Hlavní autoři: Kim, Kwangwoo, Bang, So-Young, Lee, Seunghun, Lee, Hye-Soon, Shim, Seung-Cheol, Kang, Young Mo, Suh, Chang-Hee, Sun, Celi, Nath, Swapan K., Bae, Sang-Cheol, Kim, Tae-Hwan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662802/
https://ncbi.nlm.nih.gov/pubmed/26613595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0855-3
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