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A Perspective on Roles Played by Innate and Adaptive Immunity in the Pathobiology of Neurodegenerative Disorders

Aberrant innate and adaptive immune responses are neurodegenerative disease effectors. Disease is heralded by a generalized but subtle immune activation orchestrated by the release of extracellular prion-like aggregated and oxidized or otherwise modified proteins. These are responsible for an inflam...

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Pubblicato in:J Neuroimmune Pharmacol
Autori principali: Gendelman, Howard E., Mosley, R. Lee
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662620/
https://ncbi.nlm.nih.gov/pubmed/26520433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-015-9639-4
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