Targeting lactate transport suppresses in vivo breast tumour growth

BACKGROUND: Most cancers, including breast cancer, have high rates of glucose consumption, associated with lactate production, a process referred as “Warburg effect”. Acidification of the tumour microenvironment by lactate extrusion, performed by lactate transporters (MCTs), is associated with highe...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Morais-Santos, Filipa, Granja, Sara, Miranda-Gonçalves, Vera, Moreira, António H.J., Queirós, Sandro, Vilaça, João L., Schmitt, Fernando C., Longatto-Filho, Adhemar, Paredes, Joana, Baltazar, Fátima, Pinheiro, Céline
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662483/
https://ncbi.nlm.nih.gov/pubmed/26203664
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