The predictive value of ERCC1 and p53 for the effect of panobinostat and cisplatin combination treatment in NSCLC

Cisplatin is one of the most common chemotherapeutic drugs for non-small cell lung cancer (NSCLC). However, the response rate is limited because of drug resistance. Histone deacetylase inhibitors (HDACis), which can alter DNA accessibility by regulating chromatin structure and inducing apoptosis, ex...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Cai, Yang, Yan, Xiang, Zhang, Guoqing, Zhao, Weihong, Jiao, Shunchang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662470/
https://ncbi.nlm.nih.gov/pubmed/25944617
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