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Myeloid-Derived Suppressor Cells: Critical Cells Driving Immune Suppression in the Tumor Microenvironment

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid cells that suppress innate and adaptive immunity. MDSCs are present in many disease settings; however, in cancer, they are a major obstacle for both natural antitumor immunity and immunotherapy. Tumor and hos...

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Библиографические подробности
Опубликовано в: :Adv Cancer Res
Главные авторы: Parker, Katherine H., Beury, Daniel W., Ostrand-Rosenberg, Suzanne
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4662416/
https://ncbi.nlm.nih.gov/pubmed/26216631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.acr.2015.04.002
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