CREB Negatively Regulates IGF2R Gene Expression and Downstream Pathways to Inhibit Hypoxia-Induced H9c2 Cardiomyoblast Cell Death

During hypoxia, gene expression is altered by various transcription factors. Insulin-like growth factor-II (IGF2) is known to be induced by hypoxia, which binds to IGF2 receptor IGF2R that acts like a G protein-coupled receptor, might cause pathological hypertrophy or activation of the mitochondria-...

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Publicat a:Int J Mol Sci
Autors principals: Chen, Wei-Kung, Kuo, Wei-Wen, Hsieh, Dennis Jine-Yuan, Chang, Hsin-Nung, Pai, Pei-Ying, Lin, Kuan-Ho, Pan, Lung-Fa, Ho, Tsung-Jung, Viswanadha, Vijaya Padma, Huang, Chih-Yang
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661925/
https://ncbi.nlm.nih.gov/pubmed/26610485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161126067
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