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Application of CRISPR/Cas9 Technology to HBV

More than 240 million people around the world are chronically infected with hepatitis B virus (HBV). Nucleos(t)ide analogs and interferon are the only two families of drugs to treat HBV currently. However, none of these anti-virals directly target the stable nuclear covalently closed circular DNA (c...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Lin, Guigao, Zhang, Kuo, Li, Jinming
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661809/
https://ncbi.nlm.nih.gov/pubmed/26540039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161125950
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