VASP, zyxin and TES are tension-dependent members of Focal Adherens Junctions independent of the α-catenin-vinculin module

Mechanical forces are integrated at cadherin-based adhesion complexes to regulate morphology and strength of cell-cell junctions and organization of associated F-actin. A central mechanosensor at the cadherin complex is α-catenin, whose stretching recruits vinculin to regulate adhesion strength. The...

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Publicado no:Sci Rep
Main Authors: Oldenburg, Joppe, van der Krogt, Gerard, Twiss, Floor, Bongaarts, Annika, Habani, Yasmin, Slotman, Johan A., Houtsmuller, Adriaan, Huveneers, Stephan, de Rooij, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661603/
https://ncbi.nlm.nih.gov/pubmed/26611125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17225
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