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Cultured enterocytes internalise bacteria across their basolateral surface for, pathogen-inhibitable, trafficking to the apical compartment

In vitro- and in vivo-polarised absorptive epithelia (enterocytes) are considered to be non-phagocytic towards bacteria with invasive pathogenic strains relying on virulence factors to ‘force’ entry. Here, we report a serendipitous discovery that questions these beliefs. Thus, we uncover in well-est...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dean, Paul, Quitard, Sabine, Bulmer, David M., Roe, Andrew J., Kenny, Brendan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661573/
https://ncbi.nlm.nih.gov/pubmed/26612456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17359
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