Accelerated apoptotic death and in vivo turnover of erythrocytes in mice lacking functional mitogen- and stress-activated kinase MSK1/2

The mitogen- and stress-activated kinase MSK1/2 plays a decisive role in apoptosis. In analogy to apoptosis of nucleated cells, suicidal erythrocyte death called eryptosis is characterized by cell shrinkage and cell membrane scrambling leading to phosphatidylserine (PS) externalization. Here, we exp...

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Publicado no:Sci Rep
Main Authors: Lang, Elisabeth, Bissinger, Rosi, Fajol, Abul, Salker, Madhuri S., Singh, Yogesh, Zelenak, Christine, Ghashghaeinia, Mehrdad, Gu, Shuchen, Jilani, Kashif, Lupescu, Adrian, Reyskens, Kathleen M. S. E., Ackermann, Teresa F., Föller, Michael, Schleicher, Erwin, Sheffield, William P., Arthur, J. Simon C., Lang, Florian, Qadri, Syed M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661433/
https://ncbi.nlm.nih.gov/pubmed/26611568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17316
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