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Plasmodium falciparum adhesion domains linked to severe malaria differ in blockade of endothelial protein C receptor

Cytoadhesion of Plasmodium falciparum-infected erythrocytes to endothelial protein C receptor (EPCR) is associated with severe malaria. It has been postulated that parasite binding could exacerbate microvascular coagulation and endothelial dysfunction in cerebral malaria by impairing the protein C-E...

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Detalhes bibliográficos
Publicado no:Cell Microbiol
Main Authors: Sampath, Sowmya, Brazier, Andrew Jay, Avril, Marion, Bernabeu, Maria, Vigdorovich, Vladimir, Mascarenhas, Anjali, Gomes, Edwin, Sather, D. Noah, Esmon, Charles T., Smith, Joseph D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661071/
https://ncbi.nlm.nih.gov/pubmed/26118955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12478
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