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Microarray analyses to quantify advantages of 2D and 3D hydrogel culture systems in maintaining the native valvular interstitial cell phenotype

Valvular interstitial cells (VICs) actively maintain and repair heart valve tissue; however, persistent activation of VICs to a myofibroblast phenotype can lead to aortic stenosis. To better understand and quantify how microenvironmental cues influence VIC phenotype and myofibroblast activation, we...

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Publicado en:Biomaterials
Main Authors: Mabry, Kelly M., Payne, Samuel Z., Anseth, Kristi S.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661067/
https://ncbi.nlm.nih.gov/pubmed/26433490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.09.035
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