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Advanced Glycation End Products: A Molecular Target for Vascular Complications in Diabetes

A nonenzymatic reaction between reducing sugars and amino groups of proteins, lipids and nucleic acids contributes to the aging of macromolecules and subsequently alters their structural integrity and function. This process has been known to progress at an accelerated rate under hyperglycemic and/or...

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Библиографические подробности
Опубликовано в: :Mol Med
Главные авторы: Yamagishi, Sho-ichi, Nakamura, Nobutaka, Suematsu, Mika, Kaseda, Kuniyoshi, Matsui, Takanori
Формат: Artigo
Язык:Inglês
Опубликовано: The Feinstein Institute Press 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661053/
https://ncbi.nlm.nih.gov/pubmed/26605646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2015.00067
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