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An efficient synthesis of N-substituted 3-nitrothiophen-2-amines
A novel protocol for the synthesis of 3-nitro-N-aryl/alkylthiophen-2-amines in good yields from the reaction of α-nitroketene N,S-aryl/alkylaminoacetals and 1,4-dithiane-2,5-diol in the presence of K(2)CO(3) in refluxing ethanol is described. This transformation generates two C–C bonds in a single o...
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| Pubblicato in: | Beilstein J Org Chem |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Beilstein-Institut
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4660920/ https://ncbi.nlm.nih.gov/pubmed/26664589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.11.185 |
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