A Bayesian model for detection of high-order interactions among genetic variants in genome-wide association studies

BACKGROUND: A central question for disease studies and crop improvements is how genetics variants drive phenotypes. Genome Wide Association Study (GWAS) provides a powerful tool for characterizing the genotype-phenotype relationships in complex traits and diseases. Epistasis (gene-gene interaction),...

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Bibliographic Details
Published in:BMC Genomics
Main Authors: Wang, Juexin, Joshi, Trupti, Valliyodan, Babu, Shi, Haiying, Liang, Yanchun, Nguyen, Henry T., Zhang, Jing, Xu, Dong
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
Subjects:
Methodology Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660815/
https://ncbi.nlm.nih.gov/pubmed/26607428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-2217-6
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