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Scutellarin regulates microglia-mediated TNC1 astrocytic reaction and astrogliosis in cerebral ischemia in the adult rats

BACKGROUND: Scutellarin, an anti-inflammatory agent, effectively suppressed microglia activation in rats with middle cerebral artery occlusion (MCAO). Robust microglia activation, acute in onset, was followed by astrogliosis. This study was aimed to determine if scutellarin would also affect the rea...

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Detalhes bibliográficos
Publicado no:BMC Neurosci
Main Authors: Fang, Ming, Yuan, Yun, Rangarajan, Parakalan, Lu, Jia, Wu, Yajun, Wang, Huadong, Wu, Chunyun, Ling, Eng-Ang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660684/
https://ncbi.nlm.nih.gov/pubmed/26608466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-015-0219-6
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