TSG101, a tumor susceptibility gene, bidirectionally modulates cell invasion through regulating MMP-9 mRNA expression

BACKGROUND: Tumor susceptibility gene 101 (TSG101) was initially identified in fibroblasts as a tumor suppressor gene but subsequent studies show that TSG101 also functions as a tumor-enhancing gene in some epithelial tumor cells. Although previous studies have unraveled diverse biological functions...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Sai, Xu Bin, Makiyama, Tomohiko, Sakane, Hiroshi, Horii, Yukimi, Hiraishi, Hideyuki, Shirataki, Hiromichi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660656/
https://ncbi.nlm.nih.gov/pubmed/26608825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1942-1
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