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Defining an additivity framework for mixture research in inducible whole-cell biosensors

A novel additivity framework for mixture effect modelling in the context of whole cell inducible biosensors has been mathematically developed and implemented in R. The proposed method is a multivariate extension of the effective dose (ED(p)) concept. Specifically, the extension accounts for differen...

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Publicat a:Sci Rep
Autors principals: Martin-Betancor, K., Ritz, C., Fernández-Piñas, F., Leganés, F., Rodea-Palomares, I.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660423/
https://ncbi.nlm.nih.gov/pubmed/26606975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17200
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