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Parvalbumin-positive interneurons of the prefrontal cortex support working memory and cognitive flexibility

Dysfunction of parvalbumin (PV)-positive GABAergic interneurons (PVIs) within the prefrontal cortex (PFC) has been implicated in schizophrenia pathology. It is however unclear, how impaired signaling of these neurons may contribute to PFC dysfunction. To identify how PVIs contribute to PFC-dependent...

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Publicado en:Sci Rep
Autores principales: Murray, Andrew J., Woloszynowska-Fraser, Marta U., Ansel-Bollepalli, Laura, Cole, Katy L. H., Foggetti, Angelica, Crouch, Barry, Riedel, Gernot, Wulff, Peer
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660359/
https://ncbi.nlm.nih.gov/pubmed/26608841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16778
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