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Comprehensive functional characterization of cancer–testis antigens defines obligate participation in multiple hallmarks of cancer

Tumours frequently activate genes whose expression is otherwise biased to the testis, collectively known as cancer–testis antigens (CTAs). The extent to which CTA expression represents epiphenomena or confers tumorigenic traits is unknown. In this study, to address this, we implemented a multidimens...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Maxfield, Kimberly E., Taus, Patrick J., Corcoran, Kathleen, Wooten, Joshua, Macion, Jennifer, Zhou, Yunyun, Borromeo, Mark, Kollipara, Rahul K., Yan, Jingsheng, Xie, Yang, Xie, Xian-Jin, Whitehurst, Angelique W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660212/
https://ncbi.nlm.nih.gov/pubmed/26567849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9840
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