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Synthesis of an azido-tagged low affinity ratiometric calcium sensor

Changes in high localised concentrations of Ca(2+) ions are fundamental to cell signalling. The synthesis of a dual excitation, ratiometric calcium ion sensor with a K(d) of 90 μM, is described. It is tagged with an azido group for bioconjugation, and absorbs in the blue/green and emits in the red r...

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Detalles Bibliográficos
Publicado en:Tetrahedron
Main Authors: Caldwell, Stuart T., Cairns, Andrew G., Olson, Marnie, Chalmers, Susan, Sandison, Mairi, Mullen, William, McCarron, John G., Hartley, Richard C.
Formato: Artigo
Idioma:Inglês
Publicado: Pergamon Press 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4660056/
https://ncbi.nlm.nih.gov/pubmed/26709317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2015.10.052
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