Docosahexaenoic Acid Modulates a HER2-Associated Lipogenic Phenotype, Induces Apoptosis, and Increases Trastuzumab Action in HER2-Overexpressing Breast Carcinoma Cells

In breast cancer, lipid metabolic alterations have been recognized as potential oncogenic stimuli that may promote malignancy. To investigate whether the oncogenic nature of lipogenesis closely depends on the overexpression of HER2 protooncogene, the normal breast cell line, HB4a, was transfected wi...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biomed Res Int
Main Authors: Ravacci, Graziela Rosa, Brentani, Maria Mitzi, Tortelli, Tharcisio Citrângulo, Torrinhas, Raquel Suzana M. M., Santos, Jéssica Reis, Logullo, Angela Flávia, Waitzberg, Dan Linetzky
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659962/
https://ncbi.nlm.nih.gov/pubmed/26640797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/838652
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