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MicroRNA-200 promotes lung cancer cell growth through FOG2-independent AKT activation
MicroRNA-200 (miR-200) has emerged as a regulator of the PI3K/AKT pathway and cancer cell growth. It was reported that miR-200 can activate PI3K/AKT by targeting FOG2 (friend of GATA 2), which directly binds to the p85α regulatory subunit of PI3K. We found that miR-200 was elevated in early stage lu...
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| Publicado no: | IUBMB Life |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4659740/ https://ncbi.nlm.nih.gov/pubmed/26314828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iub.1412 |
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