A Versatile Strategy for Production of Membrane Proteins with Diverse Topologies: Application to Investigation of Bacterial Homologues of Human Divalent Metal Ion and Nucleoside Transporters

Membrane proteins play key roles in many biological processes, from acquisition of nutrients to neurotransmission, and are targets for more than 50% of current therapeutic drugs. However, their investigation is hampered by difficulties in their production and purification on a scale suitable for str...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:PLoS One
المؤلفون الرئيسيون: Ma, Cheng, Hao, Zhenyu, Huysmans, Gerard, Lesiuk, Amelia, Bullough, Per, Wang, Yingying, Bartlam, Mark, Phillips, Simon E., Young, James D., Goldman, Adrian, Baldwin, Stephen A., Postis, Vincent L. G.
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2015
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659628/
https://ncbi.nlm.nih.gov/pubmed/26606682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143010
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