Use of a High-Density Protein Microarray to Identify Autoantibodies in Subjects with Type 2 Diabetes Mellitus and an HLA Background Associated with Reduced Insulin Secretion

New biomarkers for type 2 diabetes mellitus (T2DM) may aid diagnosis, drug development or clinical treatment. Evidence is increasing for the adaptive immune system’s role in T2DM and suggests the presence of unidentified autoantibodies. While high-density protein microarrays have emerged as a useful...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chang, Douglas C., Piaggi, Paolo, Hanson, Robert L., Knowler, William C., Bucci, John, Thio, Guene, Hohenadel, Maximilian G., Bogardus, Clifton, Krakoff, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659622/
https://ncbi.nlm.nih.gov/pubmed/26606528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143551
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