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Characterization of Leukemia-Inducing Genes Using a Proto-Oncogene/Homeobox Gene Retroviral Human cDNA Library in a Mouse In Vivo Model

The purpose of this research is to develop a method to screen a large number of potential driver mutations of acute myeloid leukemia (AML) using a retroviral cDNA library and murine bone marrow transduction-transplantation system. As a proof-of-concept, murine bone marrow (BM) cells were transduced...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jang, Su Hwa, Lee, Sohyun, Chung, Hee Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659616/
https://ncbi.nlm.nih.gov/pubmed/26606454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143240
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