Impact of Pre-Analytical Variables on Cancer Targeted Gene Sequencing Efficiency

Tumor specimens are often preserved as formalin-fixed paraffin-embedded (FFPE) tissue blocks, the most common clinical source for DNA sequencing. Herein, we evaluated the effect of pre-sequencing parameters to guide proper sample selection for targeted gene sequencing. Data from 113 FFPE lung tumor...

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Vydáno v:PLoS One
Hlavní autoři: Araujo, Luiz H., Timmers, Cynthia, Shilo, Konstantin, Zhao, Weiqiang, Zhang, Jianying, Yu, Lianbo, Natarajan, Thanemozhi G., Miller, Clinton J., Yilmaz, Ayse Selen, Liu, Tom, Amann, Joseph, Lapa e Silva, José Roberto, Ferreira, Carlos Gil, Carbone, David P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659597/
https://ncbi.nlm.nih.gov/pubmed/26605948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143092
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