Impact of Pre-Analytical Variables on Cancer Targeted Gene Sequencing Efficiency

Tumor specimens are often preserved as formalin-fixed paraffin-embedded (FFPE) tissue blocks, the most common clinical source for DNA sequencing. Herein, we evaluated the effect of pre-sequencing parameters to guide proper sample selection for targeted gene sequencing. Data from 113 FFPE lung tumor...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Araujo, Luiz H., Timmers, Cynthia, Shilo, Konstantin, Zhao, Weiqiang, Zhang, Jianying, Yu, Lianbo, Natarajan, Thanemozhi G., Miller, Clinton J., Yilmaz, Ayse Selen, Liu, Tom, Amann, Joseph, Lapa e Silva, José Roberto, Ferreira, Carlos Gil, Carbone, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659597/
https://ncbi.nlm.nih.gov/pubmed/26605948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143092
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