Chronic Microdose Lithium Treatment Prevented Memory Loss and Neurohistopathological Changes in a Transgenic Mouse Model of Alzheimer's Disease

The use of lithium is well established in bipolar disorders and the benefits are being demonstrated in neurodegenerative disorders. Recently, our group showed that treatment with microdose lithium stabilized the cognitive deficits observed in Alzheimer’s disease (AD) patients. In order to verify the...

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Pubblicato in:PLoS One
Autori principali: Nunes, Marielza Andrade, Schöwe, Natalia Mendes, Monteiro-Silva, Karla Cristina, Baraldi-Tornisielo, Ticiana, Souza, Suzzanna Ingryd Gonçalves, Balthazar, Janaina, Albuquerque, Marilia Silva, Caetano, Ariadiny Lima, Viel, Tania Araujo, Buck, Hudson Sousa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659557/
https://ncbi.nlm.nih.gov/pubmed/26605788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142267
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