Phenotypic and Functional Properties of Human Steady State CD14(+) and CD1a(+) Antigen Presenting Cells and Epidermal Langerhans Cells

Cutaneous antigen presenting cells (APCs) are critical for the induction and regulation of skin immune responses. The human skin contains phenotypically and functionally distinct APCs subsets that are present at two separated locations. While CD1a(high) LCs form a dense network in the epidermis, the...

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Pubblicato in:PLoS One
Autori principali: Fehres, Cynthia. M., Bruijns, Sven C. M., Sotthewes, Brigit N., Kalay, Hakan, Schaffer, Lana, Head, Steven R., de Gruijl, Tanja D., Garcia-Vallejo, Juan J., van Kooyk, Yvette
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659545/
https://ncbi.nlm.nih.gov/pubmed/26605924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143519
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