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Preferential sites for intramolecular glucosepane cross-link formation in type I collagen: A thermodynamic study

The extracellular matrix (ECM) undergoes progressive age-related stiffening and loss of proteolytic digestibility due to an increase in concentration of advanced glycation end products (AGEs). The most abundant AGE, glucosepane, accumulates in collagen with concentrations over 100 times greater than...

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Bibliografske podrobnosti
izdano v:Matrix Biol
Main Authors: Collier, Thomas A., Nash, Anthony, Birch, Helen L., de Leeuw, Nora H.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4659457/
https://ncbi.nlm.nih.gov/pubmed/26049074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2015.06.001
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