Amyloid beta-protein as a substrate interacts with extracellular matrix to promote neurite outgrowth.
Progressive deposition of amyloid beta-protein (A beta) in brain parenchyma and blood vessels is a characteristic feature of Alzheimer disease. Recent evidence suggests that addition of solubilized synthetic A beta to medium may produce toxic or trophic effects on cultured hippocampal neurons. Becau...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1993
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46590/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8506329/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.10.4748 |
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