Oral delivery of Lactococcus lactis that secretes bioactive heme oxygenase-1 alleviates development of acute colitis in mice

BACKGROUND: Mucosal delivery of therapeutic proteins using genetically modified strains of lactic acid bacteria (gmLAB) is being investigated as a new therapeutic strategy. METHODS: We developed a strain of gmLAB, Lactococcus lactis NZ9000 (NZ-HO), which secretes the anti-inflammatory molecule recom...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Microb Cell Fact
Asıl Yazarlar: Shigemori, Suguru, Watanabe, Takafumi, Kudoh, Kai, Ihara, Masaki, Nigar, Shireen, Yamamoto, Yoshinari, Suda, Yoshihito, Sato, Takashi, Kitazawa, Haruki, Shimosato, Takeshi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2015
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658813/
https://ncbi.nlm.nih.gov/pubmed/26608030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-015-0378-2
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller