The role of Na(v)1.9 channel in the development of neuropathic orofacial pain associated with trigeminal neuralgia

BACKGROUND: Trigeminal neuralgia is accompanied by severe mechanical, thermal and chemical hypersensitivity of the orofacial area innervated by neurons of trigeminal ganglion (TG). We examined the role of the voltage-gated sodium channel subtype Na(v)1.9 in the development of trigeminal neuralgia. R...

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Veröffentlicht in:Mol Pain
Hauptverfasser: Luiz, Ana Paula, Kopach, Olga, Santana-Varela, Sonia, Wood, John N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658751/
https://ncbi.nlm.nih.gov/pubmed/26607325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12990-015-0076-4
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