ORMDL3 contributes to the risk of atherosclerosis in Chinese Han population and mediates oxidized low-density lipoprotein-induced autophagy in endothelial cells

ORMDL sphingolipid biosynthesis regulator 3 (ORMDL3) is a universally confirmed susceptibility gene for asthma and has recently emerged as a crucial modulator in lipid metabolism, inflammation and endoplasmic reticulum (ER) stress-the mechanisms also closely involved in atherosclerosis (AS). Here we...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ma, Xiaochun, Qiu, Rongfang, Dang, Jie, Li, Jiangxia, Hu, Qin, Shan, Shan, Xin, Qian, Pan, Wenying, Bian, Xianli, Yuan, Qianqian, Long, Feng, Liu, Na, Li, Yan, Gao, Fei, Zou, Chengwei, Gong, Yaoqin, Liu, Qiji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658630/
https://ncbi.nlm.nih.gov/pubmed/26603569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17194
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