Specific CEA-producing colorectal carcinoma cell killing with recombinant adenoviral vector containing cytosine deaminase gene

AIM: To kill CEA positive colorectal carcinoma cells specifically using the E coli cytosine deaminase (CD) suicide gene, a new replication-deficient recombinant adenoviral vector was constructed in which CD gene was controlled under CEA promoter and its in vitro cytotoxic effects were evaluated. MET...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Shen, Li-Zong, Wu, Wen-Xi, Xu, De-Hua, Zheng, Zhong-Cheng, Liu, Xin-Yuan, Ding, Qiang, Hua, Yi-Bing, Yao, Kun
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2002
Assuntos:
Large Intestinal Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658365/
https://ncbi.nlm.nih.gov/pubmed/11925606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v8.i2.270
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