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Disruption of IP(3)R2-mediated Ca(2+) signaling pathway in astrocytes ameliorates neuronal death and brain damage while reducing behavioral deficits after focal ischemic stroke
Inositol trisphosphate receptor (IP(3)R)-mediated intracellular Ca(2+) increase is the major Ca(2+) signaling pathway in astrocytes in the central nervous system (CNS). Ca(2+) increases in astrocytes have been found to modulate neuronal function through gliotransmitter release. We previously demonst...
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| Publicado no: | Cell Calcium |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4658295/ https://ncbi.nlm.nih.gov/pubmed/26433454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2015.09.004 |
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