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Single-molecule fluorimetry and gating currents inspire an improved optical voltage indicator

Voltage-sensing domains (VSDs) underlie the movement of voltage-gated ion channels, as well as the voltage-sensitive fluorescent responses observed from a common class of genetically encoded voltage indicators (GEVIs). Despite the widespread use and potential utility of these GEVIs, the biophysical...

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Bibliographic Details
Published in:eLife
Main Authors: Treger, Jeremy S, Priest, Michael F, Bezanilla, Francisco
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658195/
https://ncbi.nlm.nih.gov/pubmed/26599732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10482
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