The Impact of PNPLA3 rs738409 SNP on Liver Fibrosis Progression, Portal Hypertension and Hepatic Steatosis in HIV/HCV Coinfection

BACKGROUND: Faster fibrosis progression and hepatic steatosis are hallmarks of HIV/HCV coinfection. A single nucleotide polymorphism (SNP) of the PNPLA3-gene is associated with development of non-alcoholic steatohepatitis and a worse outcome in alcoholic liver disease. However, the role of PNPLA3 rs...

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Vydáno v:PLoS One
Hlavní autoři: Scheiner, Bernhard, Mandorfer, Mattias, Schwabl, Philipp, Payer, Berit Anna, Bucsics, Theresa, Bota, Simona, Aichelburg, Maximilian C., Grabmeier-Pfistershammer, Katharina, Stättermayer, Albert, Ferenci, Peter, Trauner, Michael, Peck-Radosavljevic, Markus, Reiberger, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658167/
https://ncbi.nlm.nih.gov/pubmed/26599080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143429
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