Risks of Hemolysis in Glucose-6-Phosphate Dehydrogenase Deficient Infants Exposed to Chlorproguanil-Dapsone, Mefloquine and Sulfadoxine-Pyrimethamine as Part of Intermittent Presumptive Treatment of Malaria in Infants

BACKGROUND: Chlorproguanil-dapsone (CD) has been linked to hemolysis in symptomatic glucose-6-phosphate dehydrogenase deficient (G6PDd) children. Few studies have explored the effects of G6PD status on hemolysis in children treated with Intermittent Preventive Treatment in infants (IPTi) antimalaria...

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Publicat a:PLoS One
Autors principals: Poirot, Eugenie, Vittinghoff, Eric, Ishengoma, Deus, Alifrangis, Michael, Carneiro, Ilona, Hashim, Ramadhan, Baraka, Vito, Mosha, Jacklin, Gesase, Samwel, Chandramohan, Daniel, Gosling, Roland
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658078/
https://ncbi.nlm.nih.gov/pubmed/26599634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142414
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