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A Novel MVA-Based Multiphasic Vaccine for Prevention or Treatment of Tuberculosis Induces Broad and Multifunctional Cell-Mediated Immunity in Mice and Primates

Bacille Calmette-Guérin (BCG) vaccination of new born babies can protect children against tuberculosis (TB), but fails to protect adults consistently against pulmonary TB underlying the urgent need to develop novel TB vaccines. Majority of first generation TB vaccine candidates have relied on a very...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Leung-Theung-Long, Stéphane, Gouanvic, Marie, Coupet, Charles-Antoine, Ray, Aurélie, Tupin, Emmanuel, Silvestre, Nathalie, Marchand, Jean-Baptiste, Schmitt, Doris, Hoffmann, Chantal, Klein, Murielle, Seegren, Philip, Huaman, Maria C., Cristillo, Anthony D., Inchauspé, Geneviève
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658014/
https://ncbi.nlm.nih.gov/pubmed/26599077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143552
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