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APOL1 Risk Alleles Are Associated with Exaggerated Age-Related Changes in Glomerular Number and Volume in African-American Adults: An Autopsy Study

APOL1 genetic variants contribute to kidney disease in African Americans. We assessed correlations between APOL1 profiles and renal histological features in subjects without renal disease. Glomerular number (N(glom)) and mean glomerular volume (V(glom)) were measured by the dissector/fractionator me...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Hoy, Wendy E., Hughson, Michael D., Kopp, Jeffrey B., Mott, Susan A., Bertram, John F., Winkler, Cheryl A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657832/
https://ncbi.nlm.nih.gov/pubmed/26038529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014080768
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