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Genistein, the Isoflavone in Soybean, Causes Amyloid Beta Peptide Accumulation in Human Neuroblastoma Cell Line: Implications in Alzheimer’s Disease

The isoflavone, genistein, present in soybean is being actively investigated for its potential beneficial effect against Alzheimer’s disease. Our data, however, show that in SHSY5Y cells genistein causes increased expression (mRNA and protein) of amyloid precursor protein (APP), increased mRNA expre...

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Detalhes bibliográficos
Publicado no:Aging Dis
Main Authors: Chatterjee, Gargi, Roy, Debashree, Khemka, Vineet Kumar, Chattopadhyay, Mrittika, Chakrabarti, Sasanka
Formato: Artigo
Idioma:Inglês
Publicado em: JKL International LLC 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657817/
https://ncbi.nlm.nih.gov/pubmed/26618047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2015.0327
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