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Extrinsic and intrinsic signals converge on the Runx1/CBFβ transcription factor for nonpeptidergic nociceptor maturation

The generation of diverse neuronal subtypes involves specification of neural progenitors and, subsequently, postmitotic neuronal differentiation, a relatively poorly understood process. Here, we describe a mechanism whereby the neurotrophic factor NGF and the transcription factor Runx1 coordinate po...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Huang, Siyi, O'Donovan, Kevin J, Turner, Eric E, Zhong, Jian, Ginty, David D
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657622/
https://ncbi.nlm.nih.gov/pubmed/26418744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10874
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